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Quick summary

Type of medicine

Proton Pump Inhibitor (PPI)

Generic

Yes

Active Ingredient

Esomeprazole magnesium dihydrate

Effective within

Starts working within 1 hour, with full relief in a few days

Works by

Esomeprazole works by blocking the acid-producing pumps in the stomach lining, effectively reducing the amount of acid produced. By lowering acid levels, it helps prevent irritation and inflammation, reducing symptoms such as heartburn, difficulty swallowing, and discomfort caused by acid reflux. It also plays a crucial role in healing stomach ulcers and preventing them from coming back. Many people use Esomeprazole for ongoing management of acid-related conditions, as it provides long-lasting relief and protection.

Side effects

Headache, nausea, stomach pain, diarrhoea, constipation, bloating, and benign stomach polyps​

Medication details

Description

Esomeprazole Tablets are specially formulated to provide relief from acid-related conditions such as heartburn, acid reflux, and stomach ulcers. As a proton pump inhibitor (PPI), this medication helps to reduce excess stomach acid, alleviating discomfort and preventing irritation in the stomach and esophagus. Whether you suffer from frequent acid reflux or need a treatment to help heal an ulcer, Esomeprazole offers a trusted and clinically proven solution.

Always follow your healthcare provider’s guidance for safe and effective use. If you have any questions, don’t hesitate to ask your pharmacist or doctor.

Directions

For the best results, take Esomeprazole exactly as directed. It is typically taken once a day, preferably in the morning before eating. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. If you have difficulty swallowing tablets, some brands allow the tablet to be dissolved in water or opened and mixed with a small amount of soft food. Always follow your doctor’s or pharmacist’s advice regarding the correct dosage and duration of use to ensure the best outcome.

Ingredients

Each Esomeprazole tablet contains esomeprazole, the active ingredient that belongs to the proton pump inhibitor class of medications. Additional inactive ingredients may vary depending on the brand but typically include substances that help with tablet formulation and absorption. If you have allergies or specific dietary concerns, it’s best to check the ingredient list on the packaging or consult your pharmacist.

Side Effects

Like all medications, Esomeprazole may cause side effects, though not everyone experiences them. Some of the most common side effects include headaches, nausea, diarrhea, constipation, stomach pain, and bloating. Some individuals may also experience dizziness or dry mouth. Long-term use may lead to more serious effects, such as vitamin B12 deficiency, low magnesium levels, or an increased risk of bone fractures. If you experience severe symptoms like persistent stomach pain, unexplained weight loss, or difficulty swallowing, you should seek medical attention immediately.

Warnings

Before taking Esomeprazole, it’s important to consider a few precautions. Do not take this medication if you are allergic to esomeprazole or other proton pump inhibitors. If you are pregnant, breastfeeding, or taking other medications, consult your doctor before use. Long-term use should only be done under medical supervision, as it may affect nutrient absorption over time. If your symptoms persist or worsen after two weeks of use, seek medical advice to ensure the correct treatment plan.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Apr 11, 2026, 3:30 pm

How it works

Start a consultation for your condition, select a treatment option, and our in-house clinicians will review and prescribe if suitable. Expect your order within 1-3 working days.

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FAQs

Please read our FAQs page to find out more.

How long does it take for Esomeprazole to start working?

Esomeprazole begins reducing stomach acid within a few hours, but most people start noticing significant relief from heartburn and acid reflux within two to three days. However, for conditions like ulcers, it may take up to four weeks for full healing to occur. If symptoms persist beyond this period, it’s best to consult your doctor.

Can I take Esomeprazole with other medications?

Some medications, including certain antibiotics, blood thinners, and antifungal drugs, can interact with Esomeprazole. To avoid any potential interactions, it’s always a good idea to check with your doctor or pharmacist before combining it with other medicines.

What should I do if I miss a dose of Esomeprazole?

If you forget to take a dose, take it as soon as you remember. However, if it’s already close to the time for your next dose, it’s best to skip the missed one and continue with your regular schedule. Taking a double dose to make up for the missed one is not recommended, as it won’t provide additional benefits and may increase the risk of side effects.

Can I stop taking Esomeprazole once I feel better?

Even if symptoms improve, it’s important to complete the course of treatment as recommended by your doctor. Stopping too soon may cause symptoms to return. If you’ve been prescribed Esomeprazole for long-term use, consult your doctor before making any changes to your dosage or stopping treatment altogether.

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