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Quick summary

Type of medicine

Topical Cream

Works by

Providing relief and reducing discomfort associated with hemorrhoids and anal fissures

Active Ingredient

Combination of zinc oxide, bismuth subgallate, and balsam peru

Effective within

Varies; some relief may be experienced shortly after application



Side effects

Temporary irritation, mild burning sensation, dryness in the applied area

Medication details


Anusol Cream is a topical medication designed to provide relief for the discomfort and symptoms associated with various rectal conditions, including hemorrhoids (piles) and anal fissures. This cream contains a combination of active ingredients that work together to alleviate itching, swelling, and pain in the anal area. Anusol Cream is available in a convenient 23g tube and is a widely recognized and trusted over-the-counter remedy for these common rectal issues.


Using Anusol Cream is straightforward, and following the recommended directions is essential to maximize its effectiveness and minimize potential side effects. Here are the steps for using Anusol Cream:
Cleanse the Affected Area: Begin by gently cleaning the affected anal area with mild, unscented soap and warm water. Pat the area dry with a clean, soft cloth.
Wash Your Hands: Always wash your hands thoroughly before and after applying the cream to prevent the spread of bacteria.
Apply a Small Amount: Squeeze a small amount of Anusol Cream (approximately the size of a pea) onto your fingertip or the applicator provided.
Gently Apply: Carefully apply the cream to the affected area around the anus, ensuring even coverage. Avoid inserting the cream into the rectum.
Repeat as Directed: Use Anusol Cream according to the package instructions, typically up to three times a day after each bowel movement and before bedtime. Follow the dosing instructions provided.
Hygiene: Maintain good hygiene practices by keeping the area clean and dry throughout the treatment period.
Duration of Use: Do not use Anusol Cream for more than seven consecutive days without consulting a healthcare professional. If your symptoms persist or worsen, seek medical advice.


Anusol Cream contains a combination of active and inactive ingredients that work together to provide relief from rectal discomfort. The active ingredients in Anusol Cream are:
Zinc Oxide: This ingredient acts as a protective barrier, helping to soothe and protect the skin around the anus.
Bismuth Subgallate: Known for its astringent properties, bismuth subgallate can help reduce itching and discomfort associated with hemorrhoids.
Balsam Peru: Balsam peru has mild antiseptic properties and can aid in reducing inflammation and itching.
In addition to the active ingredients, Anusol Cream also contains a range of inactive ingredients that contribute to the cream's texture, stability, and overall formulation.

Side Effects

Anusol Cream is generally considered safe when used as directed, but like all medications, it may cause side effects in some individuals. Common side effects associated with Anusol Cream may include:
Temporary irritation or burning sensation at the application site: This is usually mild and short-lived.
Allergic reactions: In rare cases, some individuals may experience an allergic reaction to one or more of the ingredients in Anusol Cream. If you notice any signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, discontinue use and seek immediate medical attention.
Excessive dryness or skin changes: Prolonged use of Anusol Cream may result in excessive dryness or skin changes in the treated area. If this occurs, stop using the cream and consult a healthcare professional.
Worsening of symptoms: If your symptoms worsen or do not improve after using Anusol Cream as directed, consult a healthcare provider for further evaluation and guidance.


Before using Anusol Cream, it's important to be aware of certain warnings and precautions:
Consult a Healthcare Provider: If you are pregnant, breastfeeding, or have a medical condition, consult your healthcare provider before using Anusol Cream.
Not for Internal Use: Anusol Cream is for external use only and should not be inserted into the rectum.
Avoid Contact with Eyes: Ensure that the cream does not come into contact with your eyes, as it may cause irritation.
Do Not Ingest: Anusol Cream is not meant to be ingested. Keep it out of the reach of children and pets.
Discontinue Use if Necessary: If you experience any unexpected or severe reactions to Anusol Cream, discontinue use and seek medical advice.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 5, 2023, 2:30 pm

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Please read our FAQs page to find out more.

Can Anusol Cream be used to treat external hemorrhoids only, or is it effective for internal hemorrhoids as well?

Anusol Cream is primarily designed for external hemorrhoids, as it is a topical medication. For internal hemorrhoids, alternative forms of Anusol products, such as suppositories, are available. Consult with a healthcare professional for guidance on the appropriate product for your specific condition.

Is Anusol Cream suitable for long-term use?

Anusol Cream is intended for short-term relief of discomfort associated with hemorrhoids and anal fissures. Prolonged or frequent use without medical supervision is not recommended. If you require long-term treatment, consult with a healthcare provider for a more suitable plan.

Can Anusol Cream be used for itching or discomfort in areas other than the anus?

Anusol Cream is formulated specifically for rectal use and should not be applied to other parts of the body. If you experience itching or discomfort elsewhere, consult a healthcare provider for appropriate treatment options.

Does Anusol Cream interact with other medications or topical products?

Anusol Cream is generally considered safe when used as directed. However, it's a good practice to inform your healthcare provider or pharmacist about all medications and topical products you are using to rule out any potential interactions. They can provide personalized advice based on your specific situation.

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